Multi-Cancer Detection
One blood test. Early signals across 10 cancers.
You have built a life worth protecting. Act with the same foresight you bring to everything else.
S$2,000 includes doctor consultation and report review. S$1,900 with the Core Health Test.
What's included
10 Cancers. One Test.
Together, these 10 cancers account for around two-thirds of all cancer-related deaths.
Bladder
More common with age; early changes are often silent, so timely detection matters.
Breast
One of the most common cancers in women; highly treatable when found early.
Colorectal
Usually develops silently; screening catches it before it spreads.
Esophageal
Often advances without clear symptoms; finding it sooner widens treatment options.
Stomach
Often linked to lifestyle and viral factors; early detection improves survival.
Pancreatic
Difficult to detect until late; early DNA signals are crucial.
Lung
Often symptomless until advanced; early detection saves lives.
Liver
Can develop quietly long before symptoms appear; early awareness helps.
Ovarian
Symptoms are often vague and easy to miss; early detection is challenging but important.
Prostate
One of the most common cancers in men; often slow-growing, so monitoring matters.
2 in 3cancer deaths come from these 10 types
Mosthave no routine screening pathway today
40+where the majority of cancers occurThe screening gap
Most cancers have no routine screening.
Many cancers are found only after symptoms appear. The Multi-Cancer Detection by Guardant is designed to surface signals earlier, including for cancers not covered by standard screening.
What sets Multi-Cancer Detection apart: when a signal is detected, the test gives a primary and secondary prediction of where in the body the cancer may have originated, helping guide next steps.
How it works
Simple. Precise. Powerful.
Blood Draw
One 10 ml sample collected at PROTOCOL clinics.
cfDNA extraction
Cell-free DNA is extracted from the sample.
Methylation analysis
Patterns analysed through proprietary bioinformatics.
Results
If positive, a Cancer Signal of Origin prediction.
What is cell-free DNA?
Cells release small amounts of DNA into the bloodstream. Cancer cells, if present, also release circulating tumour DNA. Multi-Cancer Detection reads the methylation patterns that distinguish one from the other.
What is DNA methylation?
Methylation is a natural chemical tag on DNA that can switch genes on or off. In cancer cells these tags differ, and the pattern can also hint at where a cancer may have started.
The science
Advanced science behind a simple blood draw.
Validated in a study presented at the 2025 ASCO Annual Meeting. Selected for the US National Cancer Institute Vanguard study.
Clinically validated
Backed by over 1 million oncology blood samples tested and more than 600 peer-reviewed publications.
Eligibility
Who should consider Multi-Cancer Detection.
You are 40 years or older
You take a proactive approach to preventive health
You have no known diagnosis of cancer
You haven't reviewed your screening plan recently
Next step
Consult with our medical team in person at 71 Robinson Road or virtually from anywhere.
Flexible, convenient, and always human.
Common Questions
What is the Multi-Cancer Detection test by Guardant Health?
It is a single blood test that looks for early signals across 10 cancers, many of which have no routine screening today. From one blood draw, it can also predict where in the body a detected signal may have originated, helping guide next steps with your doctor.
Who should consider this test?
It is intended for adults aged 40 and older who take a proactive approach to their health and have no known diagnosis of cancer. Your clinical eligibility will be determined by the medical provider with whom you have scheduled your appointment.
How much does it cost?
S$2,000, which includes your doctor consultation and report review. It is S$1,900 when purchased as an add on alongside the Core Health Test.
What happens if the test finds a signal?
A PROTOCOL doctor will talk you through the result and coordinate the appropriate follow-up, which may include imaging, specialist referral, or further diagnostic testing. A signal is not a diagnosis; it indicates that further evaluation is needed.
Does this replace my other cancer screening?
No. This test is intended to complement, not replace, guideline-recommended cancer screening such as mammograms or colonoscopies. You should continue with your age-appropriate, guideline-directed screening.
What does a negative result mean?
A negative result does not eliminate the possibility that cancer is present or may develop in the future. It is one part of a broader picture of your health, and you should continue age-appropriate, guideline-directed screening.
How do I get started?
Book an appointment through the Start Testing button. You will have a consultation with a PROTOCOL doctor, a simple blood draw at our clinic at 71 Robinson Road, and a follow-up to review your report.
The Guardant Multi-Cancer Detection test is a laboratory developed test for individuals aged 40 or older without a known diagnosis of cancer. It is intended to complement, not replace, guideline-recommended cancer screening. A negative result does not eliminate the possibility that cancer is present or will occur in the future, and individuals should continue to participate in age-appropriate, guideline-directed screening. A positive result requires confirmatory diagnostic evaluation as directed by a qualified healthcare provider. Results should be interpreted in the context of other clinical information by a qualified medical professional.
