Cancer Screening
Cancer Screening in Singapore, Beyond the Standard Tests.
Singapore’s national programme screens for three cancers. Most of the rest have no routine pathway at all. This looks for early signals across ten, from a single blood draw.
S$2,000 includes doctor consultation and report review. S$1,900 with the Core Health Test.
Screening by type
Cancer screening in Singapore, by type.
Ten cancers, which together account for around two thirds of all cancer deaths. For each one, what screening exists in Singapore today, and where a blood signal fits.
Bladder
No national screening programme covers bladder cancer. Early changes are usually silent, so there is no routine point at which it gets picked up.
Breast
Mammography remains the standard and you should continue it on schedule. A blood signal sits alongside it, never in place of it.
Colorectal
FIT and colonoscopy remain the standard from age 50. A blood signal is an addition between scopes, not a substitute for one.
Esophageal
No routine screening pathway exists in Singapore. It often advances without clear symptoms, so an earlier signal widens the options.
Stomach
No national screening programme covers stomach cancer here. Risk is raised by H. pylori infection and family history.
Pancreatic
No screening test is offered routinely, anywhere. It is usually found late, which is why an early signal matters so much.
Lung
Low dose CT is offered only to people at high risk from smoking. Everyone else has no screening pathway at all.
Liver
Ultrasound surveillance is offered to people with hepatitis B, hepatitis C or cirrhosis. Outside that group there is no routine check.
Ovarian
There is no effective screening test for ovarian cancer. Symptoms are vague and easily mistaken for something else.
Prostate
PSA testing is a conversation with your doctor rather than a national programme. A blood signal adds a second view.
2 in 3cancer deaths come from these 10 types
Mosthave no routine screening pathway today
40+where the majority of cancers occurRead this first
What this does not replace.
Mammography, colonoscopy and cervical screening remain the standard of care in Singapore, and you should keep to them on schedule. A blood based test is an addition, not a substitute. Its value is in the many cancers that have no routine screening pathway at all, and in giving a second view on those that do.
A signal is not a diagnosis. It means further evaluation is needed, and a PROTOCOL doctor will guide what comes next. Equally, a result that finds no signal does not rule cancer out, and it does not change what your age appropriate screening should be.
The screening gap
Singapore screens for two of them.
These are the ten cancers this test looks at. Two have a national screening programme. The rest are usually found only once symptoms appear.
One blood draw looks across all ten, including the five with nowhere else to look.
How it works
Simple. Precise. Powerful.
Blood Draw
One 40 ml sample collected at PROTOCOL clinics.
cfDNA extraction
Cell-free DNA is extracted from the sample.
Methylation analysis
Patterns analysed through proprietary bioinformatics.
Results
If positive, a Cancer Signal of Origin prediction.
If a signal is found
The test does not just say yes. It says where to look.
A signal on its own would send you searching the whole body. Multi-Cancer Detection names the two most likely origins, so your doctor knows which scan or referral comes first.
What is cell-free DNA?
Cells release small amounts of DNA into the bloodstream. Cancer cells, if present, also release circulating tumour DNA. Multi-Cancer Detection reads the methylation patterns that distinguish one from the other.
What is DNA methylation?
Methylation is a natural chemical tag on DNA that can switch genes on or off. In cancer cells these tags differ, and the pattern can also hint at where a cancer may have started.
The science
Advanced science behind a simple blood draw.
Validated in a study presented at the 2025 ASCO Annual Meeting. Selected for the US National Cancer Institute Vanguard study.
Clinically validated
Backed by over 1 million oncology blood samples tested and more than 600 peer-reviewed publications.
Eligibility
Who should consider Multi-Cancer Detection.
You are 40 years or older
You take a proactive approach to preventive health
You have no known diagnosis of cancer
You haven't reviewed your screening plan recently
Next step
Consult with our medical team in person at 71 Robinson Road or virtually from anywhere.
Flexible, convenient, and always human.
Common Questions
What is the Multi-Cancer Detection test by Guardant Health?
It is a single blood test that looks for early signals across 10 cancers, many of which have no routine screening today. From one blood draw, it can also predict where in the body a detected signal may have originated, helping guide next steps with your doctor.
Who should consider this test?
It is intended for adults aged 40 and older who take a proactive approach to their health and have no known diagnosis of cancer. Your clinical eligibility will be determined by the medical provider with whom you have scheduled your appointment.
How much does it cost?
S$2,000, which includes your doctor consultation and report review. It is S$1,900 when purchased as an add on alongside the Core Health Test.
What happens if the test finds a signal?
A PROTOCOL doctor will talk you through the result and coordinate the appropriate follow-up, which may include imaging, specialist referral, or further diagnostic testing. A signal is not a diagnosis; it indicates that further evaluation is needed.
Does this replace my other cancer screening?
No. This test is intended to complement, not replace, guideline-recommended cancer screening such as mammograms or colonoscopies. You should continue with your age-appropriate, guideline-directed screening.
What does a negative result mean?
A negative result does not eliminate the possibility that cancer is present or may develop in the future. It is one part of a broader picture of your health, and you should continue age-appropriate, guideline-directed screening.
How do I get started?
Book an appointment through the Start Testing button. You will have a consultation with a PROTOCOL doctor, a simple blood draw at our clinic at 71 Robinson Road, and a follow-up to review your report.
The Guardant Multi-Cancer Detection test is a laboratory developed test for individuals aged 40 or older without a known diagnosis of cancer. It is intended to complement, not replace, guideline-recommended cancer screening. A negative result does not eliminate the possibility that cancer is present or will occur in the future, and individuals should continue to participate in age-appropriate, guideline-directed screening. A positive result requires confirmatory diagnostic evaluation as directed by a qualified healthcare provider. Results should be interpreted in the context of other clinical information by a qualified medical professional.
