TheEvidence

by PROTOCOL

Science based writing on longevity, cancer, nutrition, supplements, hormones and preventive care. Written by our doctors, researchers and coaches. Every article carries a named clinician and the date it was last reviewed.

HRT is not one treatment. The hormone, the dose, the route and...
Hormones
ExplainerHormones

HRT: what it is, and who it actually suits

HRT is not one treatment. The hormone, the dose, the route and the timing all change who it suits.

Dr Edith Loo, Lead Clinician · 21 August 2026
ExplainerMetabolic Health

Fasting insulin: the marker that moves years before glucose

Glucose tells you the result. Fasting insulin tells you what it cost to get there, and it moves years earlier.

Dr Edith · 21 August 2026 · 1 min
ExplainerNutrition

Protein after 40: the requirement rises, appetite falls

From your forties the requirement rises while appetite falls. Most people notice neither until strength is already gone.

Agnes · 21 August 2026 · 1 min
OpinionUnderstanding Your Results

What does Screen for Life cover?

Screen for Life is Singapore's national screening programme. It covers the essentials, and it is worth knowing where it stops.

Mehdi · 21 August 2026 · 1 min
ExplainerHormones

Testosterone: what your result means

Testosterone affects energy, mood, muscle and libido. One reading is a starting point, not a verdict.

Dr Bryan · 21 August 2026 · 1 min
ExplainerUnderstanding Your Results

hs-CRP: the inflammation marker panels miss

hs-CRP measures low grade inflammation linked to risk of heart disease. Most standard panels leave it out.

Dr Bryan · 21 August 2026 · 1 min
ExplainerFitness & Body Composition

What is a good VO2 max?

VO2 max is how well your body uses oxygen when you push hard. It is closely linked to how long and how...

Agnes · 21 August 2026 · 1 min
ExplainerLongevity Science

Biological age: what the number is actually measuring

Biological age estimates how worn your body seems, not how long you have lived. It is a statistical guess built from biological...

Dr Denis · 21 August 2026 · 1 min
ExplainerImmunity & Vaccination

HPV vaccination: what it protects against

The HPV vaccine lowers the risk of the infections behind most cervical cancer. The evidence for it is strong and it works...

Dr Denis · 21 August 2026 · 1 min
ExplainerCancer Screening

Tumour markers: what they can and cannot tell you

Tumour markers are blood proteins, not cancer tests on their own. A raised result raises a question, not an answer.

Dr Edith · 21 August 2026 · 1 min
ExplainerHeart & Vascular

Lp(a): the inherited risk you test once

Lp(a) is set by your genes and barely changes through life. Testing it once tells you something cholesterol cannot.

Dr Edith · 21 August 2026 · 1 min
ExplainerUnderstanding Your Results

ApoB: the number that predicts heart risk

ApoB counts the particles that drive heart disease. It can tell you more about your risk than cholesterol alone.

Dr Edith · 21 August 2026 · 1 min
ExplainerMetabolic Health

Fatty liver in Singapore: what the scan and the bloods show

Fatty liver affects roughly one in three adults. Most have no symptoms, and in Asian populations it appears at weights that look...

Dr Edith · 5 August 2026 · 1 min
Coming January 2027

The Evidence Report

Once a year, every January, we publish what our own patient data shows. Prevalence across the markers we test, what changed for members who retested, and what we got wrong. The first edition lands January 2027.

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One email, every other week.

What we published, what we read, and the one thing worth changing. Nothing to buy.

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